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If there were only one truth, you couldn’t paint a hundred canvases on the same theme

I saw this quote at an exhibition of the work of Picasso and Cezanne in Aix en Provence. You only need to think about Cezanne’s paintings of Mont St Victoire to understand this. Or think of Picasso’s re-working of the themes of other great painters…Manet, Goya, and so on.

I find this also extremely applicable in health care. A patient never has only one story to tell, because as human beings, life is not like that. Not only is every patient’s story fascinating, but I find every time I meet a patient there’s a new story to hear and explore. Truth is never single. And it’s never complete. It’s always worth taking another perspective, hearing another story, exploring from a different angle

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The treatment of infectious diseases is often presented as one of the great success stories of modern medicine. There’s no doubt that antibiotics have the potential to kill many bacteria in life threatening situations and so have saved many lives. Antivirals don’t have as good a success rate as antibiotics (despite the strange current craze for dishing out Tamiflu). However, the story of infectious disease is not so simple. I came across a feature about this on the BBC site the other day, headed “Are we losing the war on bugs?” This is typical language about the issue of infection – it is presented as a war, which is about as helpful a metaphor as the “war on drugs” or the “war on terror”. If these are wars, then when could we reasonably expect them to be over? In fact, the BBC article is the most heavily war metaphor laden article on infectious disease I’ve read for a long time.

And indeed our battle to outwit the bacteria which have caused death and decimation down the centuries has revealed just what a formidable foe they can be.
It is a war of attrition. There have been points where we have been advancing, and points when we have had to beat a retreat.
In part is the ability to keep people alive for longer which has enabled some bugs to find a chink in our armour
Influenza is seen as the most wily of viruses, constantly adapting to thwart our attempts to combat it.
We will always be at war with microbes. Their genetic promiscuity is impressive, but we are learning more about them all the time. They are versatile and enduring – but so are we

Many of those phrases are direct quotes from scientists working in this area, so it isn’t only the journalist who has bought into this metaphor. Is this a helpful way to think about infection? I don’t think so. The clue lies in that last quote about microbes being “versatile and enduring” and the admission that it isn’t the kind of war which can be won.

Bacteria and viruses are part Nature, just as we are. We have a complex relationship with them. We couldn’t live without them and sometimes we can’t live with them. So what exactly is the situation? Having invented antibiotics have we discovered how to control infectious disease? Because that’s what the war metaphor is all about. It’s that dominant scientism belief that Man can conquer and control Nature. Scientifically, and philosophically, I think that’s a foolish stance.

I recently came across a research article from 2000, written by Mitchell Cohen, and published in Nature Insight (Volume 406(6797), 17 August 2000, pp 762-76). The article is entitled “Changing patterns of infectious disease” (no war metaphor, unlike the BBC piece)
Here’s the abstract

Despite a century of often successful prevention and control efforts, infectious diseases remain an important global problem in public health, causing over 13 million deaths each year. Changes in society, technology and the microorganisms themselves are contributing to the emergence of new diseases, the re-emergence of diseases once controlled, and to the development of antimicrobial resistance. Two areas of special concern in the twenty-first century are food-borne disease and antimicrobial resistance. The effective control of infectious diseases in the new millennium will require effective public health infrastructures that will rapidly recognize and respond to them and will prevent emerging problems

The author points out that at the beginning of the 20th century infectious diseases were the leading causes of death worldwide, and that average life expectancy was only 47 largely due to the number of children who died in infancy from infections. However, he then goes on to point out that from 1700 to 1900 life expectancy had risen in Britain from 17 to 52 and that the death rate from TB had fallen by 80%. Antibiotics hadn’t been invented yet.
The reasons for the change were “primarily decreases in host susceptibility and/or disease transmission.” After the invention of antibiotics infectious disease became even less of a cause of death “Between 1900 and 1980, mortality from infectious disease fell from 797 to 36 per 100,000” “By the end of the twentieth century, in most of the developed world, mortality from infectious diseases had been replaced by mortality from chronic illnesses such as heart disease, cancer and stroke” (war on chronic disease anyone?)
However, it’s a more complex picture, with new infections, and old infections now resistant to previously effective treatments. 13 million people died from infections in 1998, and the death rates from infectious disease have risen even in developed countries. Why? The conclusion reached by this particular author is interesting “The recurring theme throughout all of these factors that influence the emergence of infectious diseases is change”. What changes? Well, too many to cover here actually, but not least changes in demographics with increasing numbers of vulnerable people, from the elderly to the malnourished; changing patterns of human behaviour with more children being cared for in groups in nurseries, and more international travel; changes in the amount of ready-prepared foods being eaten placing food safety out of the hands of individuals and into industry and commerce; and the over-prescribing of antimicrobial drugs rises in resistance.

So the war metaphor doesn’t really work. The problem turns out to be more complex than beating the baddies. The best explanations for disease patterns emerge from understandings of how we live in this world. Yes, we do need drugs to treat life threatening infectious disease but the biggest advances will come from attending to our adaptability and our resilience. As a species we need to learn what influences these characteristics and to take measures to increase them. So here’s your challenge. What do you think can increase adaptability and resilience? At a personal level, and at a global level?

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How accurate are the published figures about swine flu?

Once the decision was taken to skip swabs and diagnose on symptoms only, the figures have likely to have become very unreliable. Is anyone objectively studying the percentage of those who have a swine flu diagnosis from the questionnaire only, who actually have evidence of swine flu virus, so we can understand just how accurate, or inaccurate the figures are? Reports such as “100,000 new cases of swine flu last week alone” do indeed generate alarm. What are the real figures? If nobody is interested to discover the real figures then maybe at least the reporting should be changed to “100,000 new cases of flu-like illnesses last week”, or something similar.

Why are so many patients being prescribed Tamiflu? What we know about Tamiflu is that it may be able to delay the spread of the virus for a short period of time (but not prevent it’s spread ultimately); that it can shorten the duration of the illness by about a day [Treanor JJ, Hayden FG, Vrooman PS, et al. Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. JAMA. 2000;283:1016-1024] (but not that it can save lives or even prevent serious complications of the flu); that it is “an unpleasant experience” to take with side effects ranging from nausea, vomiting, and hallucinations to serious, rare effects like Stevens-Johnson Syndrome and toxic epidermal necrolysis .

As we have no evidence that it is safe to take in pregnancy, and best practice would therefore suggest that it should only be prescribed when there is significant threat to the foetus, but that’s not the standard being used. An interview with a pregnant woman on BBC news last week showed her picking up her Tamiflu even though she personally thought she only had a cold, because she’d been advised to take the medication on the basis of “better safe than sorry”.

Finally, if seasonal flu kills 8,000 to 9,000 people every year in England, (and up to 19,000 in 2002), is the management of swine flu leading to a different way of dealing with seasonal flu in the future? Will we now see seasonal flu diagnosable online and by telephone by non-medical staff and the mass prescribing of Tamiflu every winter?

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That famous line from Burns’ “To a Louse”…….Oh wad some power the giftie gie us, to see oursels as ithers see us – lovely sentiment, but just not possible! I was reminded of it as I read two related articles by Emily Pronin recently (published in Personality and Social Psychology Bulletin,Vol. 28 No. 3, March 2002 369-381 and the 30 MAY 2008 VOL 320 of SCIENCE Magazine)

Do you ever think why am I only person to see something rationally and reasonably, and everyone else seems biased?
Well, that’s a common experience. It’s also common to wonder why nobody really understands you, and to always fail to completely understand another person.
Why is that?
The practice of medicine is based on understanding……trying to understand what another person is experiencing in order to try and identify whether or not they are ill, and what kind of help they might need. Sounds simple, but it’s far from it.
I recently read two related articles which explain these difficulties very clearly. As with most insights, what they have to say seems clear and obvious once you read it. Both articles deal with the differences between self-knowledge and the knowledge of others.
In essence they show that for self-knowledge we have continuous access to our inner subjective experience of reality, including the full range of sensory inputs, our emotions, and our thought processes. However, when we try to have knowledge of another person we have no direct access at all to any of these phenomena. How exactly does another person perceive and experience a particular colour, or sound, or smell? What emotional experience are they having? And what are they actually thinking? We don’t know. We can’t know. We have to listen to what they have to say and watch how they behave then make our assumptions. Our assumptions, of course, are based on our perspective, not on theirs.
So it isn’t possible to know another person the way can know ourselves. On top of that, our subjective experience conveys a degree of authenticity to our sense of self, which can never be matched when interpreting the language or behaviour of another.
It’s just how things are. We function in a way which gives great weight to our subjective experience…..even our opinions and assumptions about others gain, for us, this high degree of authenticity. We have a tendency to think we can understand another person better than they can understand themselves. The reality, however, is just the reverse, and we should always doubt our understanding and judgement of others more than we do. That’s why true empathy requires a high level of humility.

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I’ve just read Passions and Tempers, by Noga Arikha (ISBN 978-0-06-073116-8)

I expect you’re familiar with the four terms, melancholic, choleric, phlegmatic and sanguine. They might not be everyday words any more but they’re certainly still common enough currency for most people to have at least some idea what they mean. They are, of course, the four temperaments, each of which is expressive of one of the four humours. Noga Arikha is a historian and this book is astonishing in its range. She begins way back in the sixth century BC and traces the idea of these humours from then right up into present time. I found the book totally absorbing and convincing, not just because of the fascinating story of both the persistence and the development of this ancient idea, but because of the meta-narratives……what this particular history tells us about what it is to be human, what it is to be a physician, and how strong ideas can evolve with the expansion of human knowledge rather than be destroyed by that process.
The book is divided into seven main sections (and given Noga’s deep familiarity with cultural rhythms and divisions, I wouldn’t be surprised if this very structure wasn’t a nod towards the seven ages of Man!). Each section describes the humours in a period of history from antiquity right up to the end of twentieth century. Before I read this book I thought the humours were an interesting extinct idea, and it was the invention of the thermometer in the 17th century which did for them. I understood that when the body temperature of a choleric was compared to that of a phlegmatic type and found to be the same, that the theory was discredited. I now know that analysis was not only simplistic, it was wrong! I also thought that the autopsies performed in the great 16th and 17th century Parisian Public hospitals made the morbid anatomist the great medical authorities and turned illness from being a holistic imbalance, to being a physical disease which could be seen, touched and measured in the body (see The Anatomy Lesson of Dr Tulp) That too turns out to be way too simplistic an understanding.
Humoural theory was indeed a holistic one where the proportions and flows of the humours within a person were thought to be connected to, or influenced by, the environment in which that person lived, which was, in turn, intimately connected with the movements of the Cosmos. The humours themselves were invisible but there were plenty of theories created to explain their behaviour and significance. Dissections and, horrifically, vivisections performed back in third century BC not only developed our understanding of anatomy, but by both failing to show any humours, and by providing alternative, observable explanations for illness, began a train of thought which was indeed to take off in the 17th century with Descartes’ separation of the body from the mind, and in the 18th century with Julien-Offray de la Metrie’s description of Man as a Machine (L’homme-machine) becoming the dominant mode of thought in scientific medicine right up to the present day.
However, as Noga Arikha shows so clearly, the humours as a concept, (as opposed to humours as material entities), still help us to understand the body and the mind as one, not two, and to seek to explain the links between the various parts of the body and the mind. The fact that such modern ideas, as described by researchers in “psychoneuroimmunology”, and philosophers and neuroscientists who discuss the embodied nature of the mind, has such ancient roots is quite breath-taking.
As she says in the introduction…..

….there was a continuum between passions and cognition, physiology and psychology, individual and environment.

Even in Hippocratic writings we read…

every part of the body, on becoming ill, immediately produces disease in some other part.

and

Men do not understand how to observe the invisible through the visible.

Let me just share with you two features of ancient practice which I found highly thought provoking and relevant to current medical practice.
From the sixth to the second centuries BC Asklepieia were the temples of the healer who became a god, Asklepios. One particulary famous one was in his birthplace, Epidaurus. A sick person would have a stay in one of these Asklepieia (which were healing centres, or spas). On admission they would have a ritual bath, then settle to sleep in an area known as the “abaton”. Every morning they would discuss their dreams with the priests, and they would receive water treatments, herbs and even, if necessary, surgery. The lucky ones would be visited in their dreams by the “drakon”, a healing snake which would cure their wounds with its tongue. The patients were encouraged to write down their experiences and their case records became the basis of medical learning which the priest/healers used to develop their treatments.
I find many aspects of this quite fascinating. Don’t we still need such places of healing, where patients can be cared for (maybe we don’t use water treatments and bathing enough these days!), and where, not only can they share their dreams, but are encouraged to record their experiences of care so that health care professionals, and other patients, can learn from them? What strikes me about this story is how the focus was on health, not disease, and how the individual’s subjective experience was central to the care.
The second story which similarly provoked my thinking was captured in these two passages –

A learned doctor was one who had primarily read many books, rather than treated many patients.

Doctors could treat only symptoms that corresponded to cases which records or histories existed already.

The dominant current model is medicine is called “Evidence Based Medicine” and “evidence” is primarily published research. It stuck me as I read the first of those two sentences, that nowadays, those who claim authority in medicine are typically those who have read many articles, rather than treated many patients! Indeed I am often amazed at the pronouncements of professors who claim to know the best way to treat patients but who are not clinically active with real patients.
The second sentence stimulated two thoughts in my mind. The first was recalling what Dr Harry Burns, Chief Medical Officer of Scotland once said about his concern with the way “Evidence Based Medicine” was being used, and that was where was all the innovation to come from, if we only allowed the practice of what we already knew? The second was how difficult it is for many doctors to accept the reality of illnesses which don’t fit the models already described – chronic fatigue syndrome, and, fibromyalgia, being just two of the obvious ones.
So, I found this book stimulating and enlightening. It is a GOOD read and I think it has the potential to deepen any health care professional’s understanding of health and healing.

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In Noga Arikha’s excellent Passions and Tempers, A History of the Humours, (ISBN 978-0-06-073116-8) she traces the history of the concept of the four humours, blood, phlegm, yellow bile and black bile, across cultures and centuries. Early in the book she describes the great library in Alexandria in the third century BC. The library was part of the Museion, a real hothouse of learning and research in the city founded by Ptolemy I Soter. What I hadn’t known before about this great academy completely shocked me. Ptolemy authorised not only human dissections of cadavers, but also the vivisection of condemned criminals.

Vivisection perhaps seemed cruel and gruesome, but, he wondered, was it really so terrible to hurt a small number of criminals for the sake of finding cures for the long term, and for a large number of good people? Whether the Ptolemies used such a justification or not, anatomical knowledge sprouted from the flaying of outlaws.

That paragraph stopped me in my tracks. Can you imagine? How does a person motivated to do good by reducing the suffering wrecked by disease, get to the place of justifying the live dissection of a human being? I know it was a different culture and a different Age, but what horrified me about this story was the appalling reduction of a person to, well, a piece of meat.
But then, I’m sure you’d be quick to point out to me, such awful cruelty has far from vanished from this Earth. There are plenty of reports of torture, mutilation and murder in the daily newspapers. But it was the context which really struck me. Maybe I’m naive, but I’ve always assumed that at least one of the motivations of physicians is compassion for those who suffer. But surely those Alexandrian physicians must have completely switched off their compassion to treat other human beings this way? Surely someone like Mengele, to give an example closer to our own lifetimes, was an abhorrent exception?
There are many aspects of this issue we could explore but the main thought which occurred to me as I pondered this tale, was how the reduction of a person to a mere body seemed to be a key characteristic of this behaviour. In that light, how much more important is it for us, to maintain a holistic engagement with those who are sick, and not reduce them to only material, physical bodies?
We physicians are not technicians of the body, we human beings struggling to understand and help other human beings.
We are all more than mere bodies.
We are conscious, sentient beings; heroes not zombies.

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In this week’s BMJ there is vociferous criticism of a recent article which advocated treating everyone, yes everyone, over 55 with antihypertensives irrespective of their actual blood pressure. The authors claimed that this would be a good way to reduce heart attacks and strokes. There were a number of excellent criticisms of this suggestion and in their right to reply the authors rebuffed the claim that this would medicalise everyone over 55 with this statement –

Offering treatment to all above a specified age regardless of blood pressure does not “medicalise” people because they do not become “patients” with a medical diagnosis, but telling people they have “hypertension” does medicalise them.

Pardon? A person doesn’t become a patient unless they are given a medical diagnosis, but if they are treated with a drug they are just a person?? I’m sorry, but I don’t follow that logic.

Imagine my surprise when after putting down my BMJ I came across this quote in one of Montaigne’s essays –

…among all my acquaintance, I see no people so soon sick, and so long before they are well, as those who take much physic [drugs] their very health is altered and corrupted by their frequent prescriptions. Physicians are not content to deal only with the sick, but they will moreover corrupt health itself, for fear men should at any time escape their authority.

That’s from Montaigne’s Essais written in 1580!

I’m with Montaigne…..a medicated life is not something to aspire to! (I’m also pretty fed up with so called experts telling me they know what’s best for ME!)

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….stepped out into the garden at work and look what I found!

GHH iris

(emerveillement)

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The NHS Confederation has produced a report highlighting a potential “shortfall” in the NHS in England’s budget by 2011. I heard one of their spokeswomen on the BBC news this morning and she summarised the Confederation’s message. They are recommending more “efficiency”, better “productivity” and a reduction in the range of services offered by the NHS. In their report they make it clear that the changes will require reducing the number of NHS staff and having clinicians perform more doctor-patient interventions.
Another way of putting this is to say they think the answers lie in less staff providing a greater number of uniform interventions to more people.

I find these conclusions dehumanising. They turn subjects into objects. Health and illness are experiences. They are not events or products.

I’ve just finished reading The Postmodern Prince by John Sanbonmatsu. It covers an area of academic activity  I’m not familiar with – political critical theory. However, a few passages struck me loud and clear.

Holbach and Helvetius had portrayed “Man” as a rational, self-interested subject – and manipulable object. This rationalist view sharply separated culture and nature, subject and object, thought and feeling, and so on,

In the 1920s, Georg Lukacs elaborated Marx and Engels’ critique in his brilliant work, History and Class Consciousness, with his famous description of reification – the cultural process in capitalism by which subjects are turned into objects, and objects into seeming “subjects”, under the twin pressures of commodification and rationalisation.

What all forms of idealism, past, present, or future, have in common is the suppression of experience as the basis of human knowledge and practice.

Ethical relations, broadly speaking, depend on what Daniel Brudney calls “attentiveness to the other”. Without this attentiveness, we risk mistaking a “who” for a “what” – that is, a being or a subject for a thing – and so come to justify all manner of political violence.

Empathy – this powerful natural capacity of ours – must be held at bay, sublimated into the rationalist’s passion for dispassion.

One of the hallmarks of modernity is rationalisation, the progressive reduction of the lifeworld to quantifiable procedures and methods. But in stripping nature of its mystery, the Enlightenment disfigured the nonhuman. This, in turn, has led to our own disfigurement, a “disenchantment” as technological innovation and scientific revolution yielded ever more powerful ways of controlling human beings, and not “only” other animals.

These quotes capture, for me, the essence of something fundamentally important. Our systems are falling apart, and it strikes me that the greatest failure of our current political, economic and social systems is the way they de-humanise, the way they turn the “subject” into an “object”. It’s life-denying.

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Both Channel 4’s “more4news” and the NHS Confederation today contributed to the ongoing attack on homeopathy in the NHS by claiming that removing homeopathic care from the NHS would make a useful contribution to improving the NHS finances. Are they serious?

According to more4news the NHS in England spent about £3.5 million pounds a year on homeopathic care for about 22,000 patient “episodes” a year (both outpatient and inpatient care).

In 2007-2008 there were 54.3 million outpatient attendances (“episodes”) in England.

In 2005 an estimated £320 million pounds was spent by the NHS in England on management consultants.

The NHS drug bill is £7.2 BILLION.

Adverse drug effects from these prescribed drugs cost an estimated £466 million to treat in the NHS in England in 2006.

Bit of perspective guys? If you’re looking for answers to the financial problems of the NHS, you’re not going to find them in denying access to a therapy chosen by patients with long term conditions. Those patients aren’t going to go away. They’ll just need treated with something more expensive, and more likely to cause harm, than the care they’re currently receiving from their NHS homeopathic clinics.

In the real world, there are no single treatments which are guaranteed to work in every single patient with the same illness. In the NHS, as in Nature, we need diversity because, actually, we’re not all the same.

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